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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM81073
Substrate
n/a
Meas. Tech.
Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase
IC50
24300±n/a nM
Citation
 PubChem, PC Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase PubChem Bioassay (2011)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD | G6PD_HUMAN | Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b
Type:
Enzyme
Mol. Mass.:
59258.58
Organism:
Homo sapiens (Human)
Description:
P11413
Residue:
515
Sequence:
MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
  
Inhibitor
Name:
BDBM81073
Synonyms:
1,2-dihydroacenaphthylen-5-yl-[1-[(3,5-dimethoxy-4-oxidanyl-phenyl)methyl]piperidin-3-yl]methanone | 1,2-dihydroacenaphthylen-5-yl-[1-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-3-piperidinyl]methanone | 1,2-dihydroacenaphthylen-5-yl-[1-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]piperidin-3-yl]methanone | 1,2-dihydroacenaphthylen-5-yl[1-(4-hydroxy-3,5-dimethoxybenzyl)piperidin-3-yl]methanone | MLS000862689 | SMR000319589 | acenaphthen-5-yl-[1-(4-hydroxy-3,5-dimethoxy-benzyl)-3-piperidyl]methanone | cid_16187927
Type:
Small organic molecule
Emp. Form.:
C27H29NO4
Mol. Mass.:
431.5235
SMILES:
COc1cc(CN2CCCC(C2)C(=O)c2ccc3CCc4cccc2c34)cc(OC)c1O
Structure:
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