Reaction Details
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Report a problem with these dataTarget
cAMP-dependent protein kinase type II-beta regulatory subunit
Ligand
BDBM81294
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R2B (PKA-R2B) complex
EC50
66909±n/a nM
Citation
PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for activators of the Protein Kinase A-R2B (PKA-R2B) complex PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
cAMP-dependent protein kinase type II-beta regulatory subunit
Synonyms:
KAP3_HUMAN | PRKAR2B
Type:
PROTEIN
Mol. Mass.:
46282.41
Organism:
Homo sapiens (Human)
Description:
EBI_11972
Residue:
418
Sequence:
MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGTARFGHEGRTWGDLGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAPADAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
Inhibitor
Name:
BDBM81294
Synonyms:
3-[(2,4-dichlorobenzyl)sulfanyl]-2-thiophenecarboxylic acid | 3-[(2,4-dichlorobenzyl)thio]-2-thenoic acid | 3-[(2,4-dichlorophenyl)methylsulfanyl]thiophene-2-carboxylic acid | 3-[(2,4-dichlorophenyl)methylthio]-2-thiophenecarboxylic acid | MLS000328052 | SMR000168585 | cid_1480284
Type:
Small organic molecule
Emp. Form.:
C12H8Cl2O2S2
Mol. Mass.:
319.227
SMILES:
OC(=O)c1sccc1SCc1ccc(Cl)cc1Cl
Structure:
