Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM50130257
Substrate
n/a
Ki
250±n/a nM
Comments
PDSP_2804
Citation
 Burt, DR; Creese, I; Snyder, SH Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes. Mol Pharmacol 12:800-12 (1976) [PubMed] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
D(1A) dopamine receptor | D1AR | DOPAMINE D1 | DRD1 | DRD1_BOVIN | Dopamine receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49330.65
Organism:
BOVINE
Description:
DOPAMINE D1 DRD1 BOVINE::Q95136
Residue:
446
Sequence:
MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50130257
Synonyms:
(3E)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine | (E)-chlorprothixene | CHEMBL90125 | CHLORPROTHIXENE | Chlorprothixene (cis)
Type:
Small organic molecule
Emp. Form.:
C18H18ClNS
Mol. Mass.:
315.86
SMILES:
CN(C)CC\C=C1/c2ccccc2Sc2ccc(Cl)cc12
Structure:
Search PDB for entries with ligand similarity: