Reaction Details Report a problem with these data
Target
Histamine H2 receptor
Ligand
BDBM81541
Substrate
n/a
Ki
0.2±n/a nM
Comments
PDSP_1677
Citation
 Hill, SJ Multiple histamine receptors: properties and functional characteristics. Biochem Soc Trans 20:122-5 (1992) [PubMed]  Article 
Target
Name:
Histamine H2 receptor
Synonyms:
Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_CAVPO | Histamine H2-Gs alpha S
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40567.22
Organism:
Cavia porcellus (domestic guinea pig)
Description:
For the H2 receptor-binding assays, guinea pig striatum was used.
Residue:
359
Sequence:
MAFNGTVPSFCMDFTVYKVTISVILIILILVTVAGNVVVCLAVGLNRRLRSLTNCFIVSLAVTDLLLGLLVLPFSAIYQLSCKWSFSKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLITPARVAISLVFIWVISITLSFLSIHLGWNSRNETSKDNDTIVKCKVQVNEVYGLVDGLVTFYLPLLIMCITYFRIFKIAREQARRINHIGSWKAATIREHKATVTLAAVMGAFIICWFPYFTVFVYRGLKGDDAVNEVFEDVVLWLGYANSALNPILYAALNRDFRTAYHQLFCCRLASHNSHETSLRLNNSQLNRSQCQEPRWQEDKPLNLQVWSGTEVTAPQGATNR
  
Inhibitor
Name:
BDBM81541
Synonyms:
CAS_195530 | NSC_195530 | S-Beta-Dimethylhistamine-R-alpha
Type:
Small organic molecule
Emp. Form.:
C7H13N3
Mol. Mass.:
139.1982
SMILES:
CC(N)C(C)c1cnc[nH]1
Structure:
Search PDB for entries with ligand similarity: