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Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM21393
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_205
Citation
 Matsumoto, I; Combs, MR; Jones, DJ Characterization of 5-hydroxytryptamine1B receptors in rat spinal cord via [125I]iodocyanopindolol binding and inhibition of [3H]-5-hydroxytryptamine release. J Pharmacol Exp Ther 260:614-26 (1992) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B
Type:
Protein
Mol. Mass.:
43173.33
Organism:
Rattus norvegicus (Rat)
Description:
P28564
Residue:
386
Sequence:
MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
  
Inhibitor
Name:
BDBM21393
Synonyms:
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol | 8-Hydroxy-2-(di-n-propylamino)tetralin | 8-OH-DPAT | 8-OH-DPAT,(+) | 8-OH-DPAT,(-) | 8-hydroxy-N,N-dipropylaminotetralin | CHEMBL1788118 | CHEMBL505765 | CHEMBL56 | DPAT | US10562853, Compound 8-OH-DPAT | [3H]-8-OH-DPAT | cid_1220
Type:
radiolabeled ligand
Emp. Form.:
C16H25NO
Mol. Mass.:
247.3758
SMILES:
CCCN(CCC)C1CCc2cccc(O)c2C1
Structure:
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