Reaction Details Report a problem with these data
Target
Glutamate receptor 3
Ligand
BDBM81878
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_3409
Citation
 Madsen, U; Ferkany, JW; Jones, BE; Ebert, B; Johansen, TN; Holm, T; Krogsgaard-Larsen, P NMDA receptor agonists derived from ibotenic acid. Preparation, neuroexcitation and neurotoxicity. Eur J Pharmacol 189:381-91 (1990) [PubMed]  Article 
Target
Name:
Glutamate receptor 3
Synonyms:
GRIA3_RAT | Glur3 | Glutamate receptor 3 | Glutamate receptor ionotropic, AMPA 3 | Glutamate-AMPA | Gria3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
100383.57
Organism:
RAT
Description:
Glutamate-AMPA GRIA3 RAT::P19492
Residue:
888
Sequence:
MGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI
  
Inhibitor
Name:
BDBM81878
Synonyms:
N-methyl-AMPA
Type:
Small organic molecule
Emp. Form.:
C8H12N2O4
Mol. Mass.:
200.1919
SMILES:
CNC(Cc1c(C)o[nH]c1=O)C(O)=O
Structure:
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