Reaction Details Report a problem with these data
Target
Protachykinin-1
Ligand
BDBM50035057
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_779
Citation
 Schipper, J; Tulp, MT; Sijbesma, H Neurochemical profile of eltoprazine. Drug Metabol Drug Interact 8:85-114 (1990) [PubMed]  Article 
Target
Name:
Protachykinin-1
Synonyms:
Nka | Nkna | Protachykinin-1 | Substance K | Substance P | TKN1_RAT | Tac1 | Tac2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
15007.06
Organism:
RAT
Description:
Substance K 0 RAT::P06767
Residue:
130
Sequence:
MKILVAVAVFFLVSTQLFAEEIGANDDLNYWSDWSDSDQIKEAMPEPFEHLLQRIARRPKPQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERSAMQNYERRRK
  
Inhibitor
Name:
BDBM50035057
Synonyms:
(eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine | 1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine | CHEMBL282614 | Eltoprazine
Type:
Small organic molecule
Emp. Form.:
C12H16N2O2
Mol. Mass.:
220.2676
SMILES:
C1CN(CCN1)c1cccc2OCCOc12
Structure:
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