Reaction Details Report a problem with these data
Target
Carboxypeptidase B
Ligand
BDBM81906
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
1.6e+3±n/a nM
Citation
 Fernández, D; Avilés, FX; Vendrell, J Aromatic organic compounds as scaffolds for metallocarboxypeptidase inhibitor design. Chem Biol Drug Des 73:75-82 (2009) [PubMed]  Article 
Target
Name:
Carboxypeptidase B
Synonyms:
CPB
Type:
Enzyme
Mol. Mass.:
48382.46
Organism:
Helicoverpa zea (Corn earworm moth) (Heliothis zea)
Description:
Q3T905
Residue:
429
Sequence:
MKFLLVLALCAVVYAKHEAYIGWKSYYVGVATDAQAKALEPLIQKYELDFLSHPTKSREGVVLVKPQHQAGFVQDIEAGGITYRIHADDVKRQLEFDDQLIEMQRMSSFTRTAGRQLPYDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFIDGGIHAREWISPPSVTWAIHKLVEDVTENDLLEKFDWILLPVVNPDGYKYTFTNERFWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDILHEHLARMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPYTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWEGIVVGARRAGDLFRK
  
Inhibitor
Name:
BDBM81906
Synonyms:
2-(5-(naphthalen-2-yloxy)methyl)-1,3,4-oxadiazol-2-ylthio)-1-p-tolylethanone, 5
Type:
Small organic molecule
Emp. Form.:
C22H18N2O3S
Mol. Mass.:
390.455
SMILES:
Cc1ccc(cc1)C(=O)CSc1nnc(COc2ccc3ccccc3c2)o1
Structure:
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