Reaction Details Report a problem with these data
Target
P2Y purinoceptor 2
Ligand
BDBM21220
Substrate
n/a
Ki
277±n/a nM
Comments
PDSP_1302
Citation
 Klotz, KN; Vogt, H; Tawfik-Schlieper, H Comparison of A1 adenosine receptors in brain from different species by radioligand binding and photoaffinity labelling. Naunyn Schmiedebergs Arch Pharmacol 343:196-201 (1991) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | P2RY2 | P2RY2_CRIGR | P2Y purinoceptor 2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18813.49
Organism:
HAMSTER
Description:
ADENOSINE A1 ADORA1 HAMSTER::P58825
Residue:
166
Sequence:
VHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLSLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFTLCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPL
  
Inhibitor
Name:
BDBM21220
Synonyms:
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide | Adenosine analog, 3 | Adenosine, N6-Ethyl-carboxamido | Adenosine-5-(N-ethylcarboxamide) | CHEMBL464859 | N-Ethylcarboxamidoadenosine | NECA
Type:
Antineoplastic Agent
Emp. Form.:
C12H16N6O4
Mol. Mass.:
308.2932
SMILES:
CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Structure:
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