Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Alpha-2B adrenergic receptor
Ligand
BDBM81926
Substrate
n/a
Ki
4.5±n/a nM
Comments
PDSP_1437
Citation
Weinshank, RL; Zgombick, JM; Macchi, M; Adham, N; Lichtblau, H; Branchek, TA; Hartig, PR Cloning, expression, and pharmacological characterization of a human alpha 2B-adrenergic receptor. Mol Pharmacol 38:681-8 (1990) [PubMed] More Info.:
Target
Name:
Alpha-2B adrenergic receptor
Synonyms:
ADA2B_HUMAN | ADRA2B | ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR
Type:
Enzyme
Mol. Mass.:
49964.20
Organism:
Homo sapiens (Human)
Description:
P18089
Residue:
450
Sequence:
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEEEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRRAQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRILCRPWTQTAW
Inhibitor
Name:
BDBM81926
Synonyms:
Aminoclonidine, p | CAS_66711-21-5 | NSC_51763 | p-AMINOCLONIDINE
Type:
Small organic molecule
Emp. Form.:
C9H10Cl2N4
Mol. Mass.:
245.109
SMILES:
Nc1cc(Cl)c(NC2=NCCN2)c(Cl)c1 |t:7|
Structure:
