Reaction Details
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kappa-type opioid receptor isoform 1
Ligand
BDBM81931
Substrate
n/a
Ki
0.1±n/a nM
Comments
PDSP_463
Citation
Benyhe, S; Varga, E; Hepp, J; Magyar, A; Borsodi, A; Wollemann, M Characterization of kappa 1 and kappa 2 opioid binding sites in frog (Rana esculenta) brain membrane preparation. Neurochem Res 15:899-904 (1990) [PubMed] Article More Info.:
Target
Name:
kappa-type opioid receptor isoform 1
Synonyms:
OPIATE Kappa | OPRK1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42362.28
Organism:
Frog
Description:
F7A0F2
Residue:
375
Sequence:
MCFNLTMKKKKECCAPACPSSCFPNTSWLLGWDDHDNVSAYPDLPLNEGNHTSISPTISVIITAVYSMVFVVGLVGNALVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTSFLMNSWPFGDVLCKIVVSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKCINICIWMLSSSVGISAIVLGGTKISDGSTECALQFPTHYWYWDTVMKMCVFIFAFIIPVFIITICYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIVCWTPIHIFVLVEALVDVPQSIAVVSIYYFCIALGYTNSSLNPILYAFLDENFKRCFKDFCFPSKHRLDRQPNSRVGNTVQDPACNRHGSQKPV
Inhibitor
Name:
BDBM81931
Synonyms:
CAM | CAS_56337-94-1 | N-cyclopropylmethylnorazidomorphine
Type:
Small organic molecule
Emp. Form.:
C20H24N4O2
Mol. Mass.:
352.4302
SMILES:
Oc1ccc2C[C@@H]3[C@@H]4CC[C@@H](N=[N+]=[N-])[C@H]5Oc1c2[C@]45CCN3CC1CC1
Structure:
