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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50176065
Substrate
n/a
Ki
10.8±n/a nM
Comments
PDSP_111
Citation
 Gies, JP; Bertrand, C; Vanderheyden, P; Waeldele, F; Dumont, P; Pauli, G; Landry, Y Characterization of muscarinic receptors in human, guinea pig and rat lung. J Pharmacol Exp Ther 250:309-15 (1989) [PubMed] 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_PIG | CHRM2 | Cholinergic, muscarinic | GPM2 | LOC100715343 | Muscarinic acetylcholine receptor M2 | Muscarinic receptor 2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51688.65
Organism:
GUINEA PIG
Description:
Cholinergic, muscarinic 0 GUINEA PIG::P06199
Residue:
466
Sequence:
MNNSTNSSNSGLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQEPVSPSLVQGRIVKPNNNNMPGSDEALEHNKIQNGKAPRDAVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIKIVTKTQKSDSCTPANTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50176065
Synonyms:
4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidinium; iodide | Acetic acid 4-[(4-acetoxy-phenyl)-pyridin-2-yl-methyl]-phenyl ester | CHEMBL168067 | CHEMBL76897
Type:
Small organic molecule
Emp. Form.:
C21H26NO2
Mol. Mass.:
324.4361
SMILES:
C[N+]1(C)CCC(CC1)OC(=O)C(c1ccccc1)c1ccccc1
Structure:
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