Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM81971
Substrate
n/a
Ki
1.7±n/a nM
Comments
PDSP_755
Citation
 Lohse, MJ; Klotz, KN; Lindenborn-Fotinos, J; Reddington, M; Schwabe, U; Olsson, RA 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX)--a selective high affinity antagonist radioligand for A1 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol 336:204-10 (1987) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM81971
Synonyms:
1,3-Diethyl-8-phenyl-3,7-dihydro-purine-2,6-dione | CAS_1328 | CHEMBL11348 | DPX | NSC_1328
Type:
Small organic molecule
Emp. Form.:
C15H16N4O2
Mol. Mass.:
284.3131
SMILES:
CCn1c2nc([nH]c2c(=O)n(CC)c1=O)-c1ccccc1
Structure:
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