Reaction Details Report a problem with these data
Target
Nicotinic acetylcholine receptor
Ligand
BDBM50047021
Substrate
n/a
Ki
9±n/a nM
Comments
PDSP_1085
Citation
 Lippiello, PM; Fernandes, KG The binding of L-[3H]nicotine to a single class of high affinity sites in rat brain membranes. Mol Pharmacol 29:448-54 (1986) [PubMed] 
Target
Name:
Nicotinic acetylcholine receptor
Synonyms:
Nicotinic acetylcholine receptor | n-AChR
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2478.99
Organism:
RAT
Description:
n-AChR 0 RAT::Q62594
Residue:
23
Sequence:
MTMALLGTLLLLALFGRSQGKNE
  
Inhibitor
Name:
BDBM50047021
Synonyms:
2-(6-(2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone | 2-[6-(2-Hydroxy-2-phenyl-ethyl)-1-methyl-piperidin-2-yl]-1-phenyl-ethanone | 2-[6-(2-Hydroxy-2-phenyl-ethyl)-1-methyl-piperidin-2-yl]-1-phenyl-ethanone (lobeline) | CHEMBL15476 | Lobeline | Lobeline, (-) | Lobeline,Alpha
Type:
Small organic molecule
Emp. Form.:
C22H27NO2
Mol. Mass.:
337.4553
SMILES:
CN1C(CC(O)c2ccccc2)CCCC1CC(=O)c1ccccc1
Structure:
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