Reaction Details Report a problem with these data
Target
Nicotinic acetylcholine receptor
Ligand
BDBM50000690
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_1927
Citation
 Lippiello, PM; Fernandes, KG The binding of L-[3H]nicotine to a single class of high affinity sites in rat brain membranes. Mol Pharmacol 29:448-54 (1986) [PubMed] 
Target
Name:
Nicotinic acetylcholine receptor
Synonyms:
Nicotinic acetylcholine receptor | n-AChR
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2478.99
Organism:
RAT
Description:
n-AChR 0 RAT::Q62594
Residue:
23
Sequence:
MTMALLGTLLLLALFGRSQGKNE
  
Inhibitor
Name:
BDBM50000690
Synonyms:
10,25-dimethoxy-15,15,30-trimethyl-(1S,16R)-7,23-dioxa-15,30-diazoniaheptacyclo[22.6.2.23,6.112,16.118,22.08,36.027,31]hexatriaconta-3,5,8,10,12(36),18,20,22(35),24(32),25,27(31),33-dodecaene-9,21-diol,dichloride(tubocurarine) | CHEMBL501646 | Tubocurarine | Tubocurarine dichloride | Tubocurarine,d
Type:
Small organic molecule
Emp. Form.:
C37H42N2O6
Mol. Mass.:
610.7381
SMILES:
COc1cc2CC[N+](C)(C)[C@@H]3Cc4ccc(O)c(Oc5cc6[C@H](Cc7ccc(Oc(c1O)c23)cc7)[NH+](C)CCc6cc5OC)c4 |r|
Structure:
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