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Target
Cannabinoid receptor 1
Ligand
BDBM82134
Substrate
n/a
Meas. Tech.
Binding Assay
pH
7.4±0
Temperature
298.15±0 K
Ki
553±36.1 nM
Citation
 Mazzoni, O; Diurno, MV; di Bosco, AM; Novellino, E; Grieco, P; Esposito, G; Bertamino, A; Calignano, A; Russo, R Synthesis and pharmacological evaluation of analogs of indole-based cannabimimetic agents. Chem Biol Drug Des 75:106-14 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM82134
Synonyms:
3-(Arylimino)-1-(2-morpholin-4-yl-ethyl)-1,3-dihydro-indole-2-one, 4
Type:
Small organic molecule
Emp. Form.:
C24H23N3O2
Mol. Mass.:
385.4583
SMILES:
O=C1N(CCN2CCOCC2)c2ccccc2\C1=N\c1cccc2ccccc12
Structure:
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