Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50024205
Substrate
n/a
Ki
18.19±n/a nM
Comments
PDSP_1502
Citation
 To, ZP; Bonhaus, DW; Eglen, RM; Jakeman, LB Characterization and distribution of putative 5-ht7 receptors in guinea-pig brain. Br J Pharmacol 115:107-16 (1995) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT7 | 5-HT7L | 5HT7R_CAVPO | HTR7 | Serotonin 7 (5-HT7) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49632.36
Organism:
GUINEA PIG
Description:
5-HT7 HTR7 GUINEA PIG::P50407
Residue:
446
Sequence:
MMGVNSSGRPDLYGHLHSILLPGRGLPDWSPDGGADPGVSTWTPRLLSGVPEVAASPSPSWDGTWDNVSGCGEQINYGRAEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVIPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMPKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYRIYKAARKSAAKHKFPGFPRVQPESIISLNGMVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTACSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPECVLQNSDYCRKKGHDS
  
Inhibitor
Name:
BDBM50024205
Synonyms:
3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one | 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one(Pirenperone) | CHEMBL18331 | PIRENPERONE
Type:
Small organic molecule
Emp. Form.:
C23H24FN3O2
Mol. Mass.:
393.454
SMILES:
Cc1nc2ccccn2c(=O)c1CCN1CCC(CC1)C(=O)c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: