Reaction Details Report a problem with these data
Target
Nicotinic acetylcholine receptor
Ligand
BDBM50061565
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_1187
Citation
 Houghtling, RA; Dávila-García, MI; Kellar, KJ Characterization of (+/-)(-)[3H]epibatidine binding to nicotinic cholinergic receptors in rat and human brain. Mol Pharmacol 48:280-7 (1995) [PubMed] 
Target
Name:
Nicotinic acetylcholine receptor
Synonyms:
Nicotinic acetylcholine receptor | n-AChR
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2478.99
Organism:
RAT
Description:
n-AChR 0 RAT::Q62594
Residue:
23
Sequence:
MTMALLGTLLLLALFGRSQGKNE
  
Inhibitor
Name:
BDBM50061565
Synonyms:
(+)Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amine | (+/-)Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amine | (-)Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amine | CHEMBL267936 | MECAMYLAMINE | Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amine | Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amine(Mecamylamine)
Type:
Small organic molecule
Emp. Form.:
C11H21N
Mol. Mass.:
167.2911
SMILES:
CNC1(C)C2CCC(C2)C1(C)C |TLB:3:2:8:5.6,THB:1:2:8:5.6|
Structure:
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