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Target
Muscarinic acetylcholine receptor
Ligand
BDBM82379
Substrate
n/a
Ki
1±n/a nM
Comments
PDSP_3897
Citation
 Lazareno, S; Buckley, NJ; Roberts, FF Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Mol Pharmacol 38:805-15 (1990) [PubMed] 
Target
Name:
Muscarinic acetylcholine receptor
Synonyms:
CHRM4 | Cholinergic, muscarinic M4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
53017.26
Organism:
RABBIT
Description:
Cholinergic, muscarinic M4 CHRM4 RABBIT::PPPPPP
Residue:
478
Sequence:
MANFTPVNGSSSNQSVRLVTSAHNRYETVEMVFIATVTGSLSLVTVVGNVLVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGQKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPMADKDTSNESSSGSATQNTKERPATELSTAEATTPAMSAPPLQPRTLNPASKWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
  
Inhibitor
Name:
BDBM82379
Synonyms:
BTM 1042 hydrochloride | BTM1086 | CAS_87687-13-6
Type:
Small organic molecule
Emp. Form.:
C21H25N3OS
Mol. Mass.:
367.508
SMILES:
CN1CCN(C[C@@H]2[C@@H](Sc3ccccc3NC2=O)c2ccccc2)CC1
Structure:
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