Reaction Details Report a problem with these data
Target
Neurotensin
Ligand
BDBM82419
Substrate
n/a
Ki
2000±n/a nM
Comments
PDSP_1756
Citation
 Betancur, C; Canton, M; Gully, D; Vela, G; Pélaprat, D; Rostène, W Characterization and distribution of binding sites for a new neurotensin receptor antagonist ligand, [3H]SR 48692, in the guinea pig brain. J Pharmacol Exp Ther 273:1450-8 (1995) [PubMed] 
Target
Name:
Neurotensin
Synonyms:
NEUT_CAVPO | NT | NTS | Neurotensin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
1681.93
Organism:
GUINEA PIG
Description:
NT 0 GUINEA PIG::P32560
Residue:
13
Sequence:
QLYENKSRRPYIL
  
Inhibitor
Name:
BDBM82419
Synonyms:
SR 49711
Type:
n/a
Emp. Form.:
C29H29ClN4O5
Mol. Mass.:
549.017
SMILES:
COc1cccc(OC)c1-c1cc(nn1-c1ccnc2cc(Cl)ccc12)C(=O)N[C@H](C1CCCCC1)C(O)=O |wU:29.32,(4.51,5.44,;5.54,4.29,;5.06,2.83,;3.56,2.51,;3.08,1.04,;4.11,-.1,;5.62,.22,;6.65,-.93,;6.17,-2.39,;6.09,1.68,;7.6,2,;8.08,.54,;9.62,.54,;10.09,2,;8.85,2.91,;8.85,4.45,;7.51,5.22,;7.51,6.76,;8.85,7.53,;10.18,6.76,;11.56,7.58,;12.95,6.79,;14.28,7.57,;12.95,5.19,;11.56,4.39,;10.18,5.22,;10.52,-.71,;12.05,-.55,;9.89,-2.11,;10.8,-3.36,;10.17,-4.77,;8.64,-4.93,;8.01,-6.34,;8.92,-7.58,;10.45,-7.42,;11.08,-6.01,;12.33,-3.2,;13.24,-4.45,;12.96,-1.79,)|
Structure:
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