Target
G_PROTEIN_RECEP_F1_2 domain-containing protein
Ligand
BDBM78940
Substrate
n/a
Ki
39.81071705535±n/a nM
Comments
PDSP_1219
Citation
 Schoeffter, PWaeber, C 5-Hydroxytryptamine receptors with a 5-HT6 receptor-like profile stimulating adenylyl cyclase activity in pig caudate membranes. Naunyn Schmiedebergs Arch Pharmacol 350:356-60 (1994) [PubMed]  Article 
Target
Name:
G_PROTEIN_RECEP_F1_2 domain-containing protein
Synonyms:
5-HT6 | HTR6
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47273.78
Organism:
PIG
Description:
5-HT6 HTR6 PIG::I3LCE8
Residue:
440
Sequence:
MVLAQGPVNHSTPDWESGPPSEPGGSGWVAAALCVVIALTAAANSLLIVLICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWAAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPPRALALVLSAWSLAALASFLPLLLGWHELGRVRAPAPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTAMTGQALETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIAQAVCDCVSPGLFDGLTWLGYCNSTMNPIIYPLFMRDFKRALGRFMPCPRCPREHQASLASPSMRTSHSGPRPGLSLQHVLPLPLPTNLDLDSDSGTGGSSGPQFTAQLLLPGEAARDPPLPAKATTAVNVFNVDPVEPELRLHPRGSPTN
  
Inhibitor
Name:
BDBM78940
Synonyms:
METHIOTHEPIN | MLS000859918 | Methiothepin mesylate salt | SMR000326779 | cid_3039995 | mesylic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine | methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine | methanesulfonic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine
Type:
Small organic molecule
Emp. Form.:
C20H24N2S2
Mol. Mass.:
356.548
SMILES:
CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1
Structure:
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