Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Somatostatin receptor type 5
Ligand
BDBM82465
Substrate
n/a
Ki
0.18±n/a nM
Comments
PDSP_374
Citation
Hoyer, D; Lübbert, H; Bruns, C Molecular pharmacology of somatostatin receptors. Naunyn Schmiedebergs Arch Pharmacol 350:441-53 (1994) [PubMed] Article More Info.:
Target
Name:
Somatostatin receptor type 5
Synonyms:
SOMATOSTATIN SST5 | SSR5_RAT | Somatostatin receptor | Somatostatin receptor type 5 | Sstr5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39986.50
Organism:
RAT
Description:
SOMATOSTATIN SST5 SSTR5 RAT::P30938
Residue:
363
Sequence:
MEPLSLASTPSWNASAASSGNHNWSLVGSASPMGARAVLVPVLYLLVCTVGLSGNTLVIYVVLRHAKMKTVTNVYILNLAVADVLFMLGLPFLATQNAVVSYWPFGSFLCRLVMTLDGINQFTSIFCLMVMSVDRYLAVVHPLRSARWRRPRVAKMASAAVWVFSLLMSLPLLVFADVQEGWGTCNLSWPEPVGLWGAAFITYTSVLGFFGPLLVICLCYLLIVVKVKAAGMRVGSSRRRRSEPKVTRMVVVVVLVFVGCWLPFFIVNIVNLAFTLPEEPTSAGLYFFVVVLSYANSCANPLLYGFLSDNFRQSFRKVLCLRRGYGMEDADAIEPRPDKSGRPQATLPTRSCEANGLMQTSRI
Inhibitor
Name:
BDBM82465
Synonyms:
BIM 23023 | BIM-23023 | D-Phe-L-Cys(1)-L-Tyr-D-Trp-L-Lys-L-Abu-L-Cys(1)-L-Thr-NH2
Type:
Small organic molecule
Emp. Form.:
C49H65N11O10S2
Mol. Mass.:
1032.238
SMILES:
CC[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1
Structure:
