Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 5B
Ligand
BDBM50005835
Substrate
n/a
Ki
807±n/a nM
Comments
PDSP_1788
Citation
 Wisden, W; Parker, EM; Mahle, CD; Grisel, DA; Nowak, HP; Yocca, FD; Felder, CC; Seeburg, PH; Voigt, MM Cloning and characterization of the rat 5-HT5B receptor. Evidence that the 5-HT5B receptor couples to a G protein in mammalian cell membranes. FEBS Lett 333:25-31 (1993) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 5B
Synonyms:
5-HT5B | 5-hydroxytryptamine receptor 5B | 5HT5B_RAT | 5ht5b | Htr5b | Serotonin (5-HT) receptor | Serotonin 5b (5-HT5b) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41141.95
Organism:
RAT
Description:
5-HT5B 0 RAT::P35365
Residue:
370
Sequence:
MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGREPPFSAFTVLVVTLLVLLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRWQLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRRRASALMIAITWALSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYVPLAVVLFVYWKIYKAAKFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCRATVAFQTSGDSWREQKEKRAAMMVGILIGVFVLCWIPFFLTELVSPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNNAFKSLFTKQR
  
Inhibitor
Name:
BDBM50005835
Synonyms:
(3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide | 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide | 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide | 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide | 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide | CHEMBL128 | SUMATRIPTAN | Sumatran | Sumax
Type:
Small organic molecule
Emp. Form.:
C14H21N3O2S
Mol. Mass.:
295.4
SMILES:
CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
Structure:
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