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Target
D(3) dopamine receptor
Ligand
BDBM50010289
Substrate
n/a
Ki
0.26±n/a nM
Comments
PDSP_1268
Citation
 Freedman, SB; Patel, S; Marwood, R; Emms, F; Seabrook, GR; Knowles, MR; McAllister, G Expression and pharmacological characterization of the human D3 dopamine receptor. J Pharmacol Exp Ther 268:417-26 (1994) [PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50010289
Synonyms:
(R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol | (RS)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol | (S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol | 6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol | CHEMBL109684 | N-0434
Type:
Small organic molecule
Emp. Form.:
C21H27NO
Mol. Mass.:
309.4452
SMILES:
CCCN(CCc1ccccc1)C1CCc2c(O)cccc2C1
Structure:
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