Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM82588
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3
IC50
>66000±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3 PubChem Bioassay (2011)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM82588
Synonyms:
MLS-0437602.0002 | N-[[5-[2-(1,3-benzothiazol-2-ylamino)-2-oxidanylidene-ethyl]sulfanyl-4-(3-chlorophenyl)-1,2,4-triazol-3-yl]methyl]-4-tert-butyl-benzamide | N-[[5-[2-(1,3-benzothiazol-2-ylamino)-2-oxoethyl]sulfanyl-4-(3-chlorophenyl)-1,2,4-triazol-3-yl]methyl]-4-tert-butylbenzamide | N-[[5-[[2-(1,3-benzothiazol-2-ylamino)-2-keto-ethyl]thio]-4-(3-chlorophenyl)-1,2,4-triazol-3-yl]methyl]-4-tert-butyl-benzamide | N-[[5-[[2-(1,3-benzothiazol-2-ylamino)-2-oxoethyl]thio]-4-(3-chlorophenyl)-1,2,4-triazol-3-yl]methyl]-4-tert-butylbenzamide | cid_4639048
Type:
Small organic molecule
Emp. Form.:
C29H27ClN6O2S2
Mol. Mass.:
591.147
SMILES:
CC(C)(C)c1ccc(cc1)C(=O)NCc1nnc(SCC(=O)Nc2nc3ccccc3s2)n1-c1cccc(Cl)c1
Structure:
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