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Target
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Ligand
BDBM82636
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay
IC50
8608±369 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay (2011)[AID] 
Target
Name:
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Synonyms:
CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29199.89
Organism:
Homo sapiens (Human)
Description:
gi_10864009
Residue:
261
Sequence:
MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS
  
Inhibitor
Name:
BDBM82636
Synonyms:
MLS000531721 | N-(2-tert-butylsulfanylethyl)-2,3-bis(chloranyl)-4-methoxy-benzenesulfonamide | N-(2-tert-butylsulfanylethyl)-2,3-dichloro-4-methoxybenzenesulfonamide | N-[2-(tert-butylthio)ethyl]-2,3-dichloro-4-methoxy-benzenesulfonamide | N-[2-(tert-butylthio)ethyl]-2,3-dichloro-4-methoxybenzenesulfonamide | SMR000136699 | cid_1815775
Type:
Small organic molecule
Emp. Form.:
C13H19Cl2NO3S2
Mol. Mass.:
372.331
SMILES:
COc1ccc(c(Cl)c1Cl)S(=O)(=O)NCCSC(C)(C)C
Structure:
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