Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 6
Ligand
BDBM79987
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
5220±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM79987
Synonyms:
5-(4-chlorophenyl)-N-[(2-hydroxy-5-methyl-phenyl)thiocarbamoyl]-2-furamide | 5-(4-chlorophenyl)-N-[(2-hydroxy-5-methylanilino)-sulfanylidenemethyl]-2-furancarboxamide | 5-(4-chlorophenyl)-N-[(2-hydroxy-5-methylphenyl)carbamothioyl]furan-2-carboxamide | 5-(4-chlorophenyl)-N-[(5-methyl-2-oxidanyl-phenyl)carbamothioyl]furan-2-carboxamide | 5-(4-chlorophenyl)-N-{[(2-hydroxy-5-methylphenyl)amino]carbonothioyl}-2-furamide | MLS000574038 | SMR000195626 | cid_2905078
Type:
Small organic molecule
Emp. Form.:
C19H15ClN2O3S
Mol. Mass.:
386.852
SMILES:
Cc1ccc(O)c(NC(=S)NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)c1
Structure:
Search PDB for entries with ligand similarity: