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Target
Beta-lactamase
Ligand
BDBM64173
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA)
IC50
>49762±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM64173
Synonyms:
1-(2-furanyl)-3-phenyl-2-propyn-1-one | 1-(2-furyl)-3-phenyl-prop-2-yn-1-one | 1-(furan-2-yl)-3-phenyl-prop-2-yn-1-one | 1-(furan-2-yl)-3-phenylprop-2-yn-1-one | MLS001174896 | SMR000595457 | cid_200953
Type:
Small organic molecule
Emp. Form.:
C13H8O2
Mol. Mass.:
196.2014
SMILES:
O=C(C#Cc1ccccc1)c1ccco1
Structure:
Search PDB for entries with ligand similarity: