Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM80880
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
357±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM80880
Synonyms:
7-Ethyl-5-(4-nitro-phenyl)-2-phenyl-3H-benzo[e][1,2,4]triazepine | 7-ethyl-5-(4-nitrophenyl)-2-phenyl-4H-1,3,4-benzotriazepine | MLS000566936 | SMR000177233 | cid_3135949
Type:
Small organic molecule
Emp. Form.:
C22H18N4O2
Mol. Mass.:
370.4039
SMILES:
CCc1ccc2N=C(N=[NH+][C-](c3ccc(cc3)[N+]([O-])=O)c2c1)c1ccccc1 |c:6,8|
Structure:
Search PDB for entries with ligand similarity: