Target
Delta-type opioid receptor
Ligand
BDBM83319
Substrate
n/a
Meas. Tech.
Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay
EC50
>92480±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization PubChem Bioassay (2011)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM83319
Synonyms:
1-[2-(dimethylamino)-2-(3-pyridinyl)ethyl]-3-(3-methylphenyl)thiourea | 1-[2-(dimethylamino)-2-(3-pyridyl)ethyl]-3-(m-tolyl)thiourea | 1-[2-(dimethylamino)-2-pyridin-3-yl-ethyl]-3-(3-methylphenyl)thiourea | 1-[2-(dimethylamino)-2-pyridin-3-ylethyl]-3-(3-methylphenyl)thiourea | MLS000720335 | SMR000236204 | cid_3600177
Type:
Small organic molecule
Emp. Form.:
C17H22N4S
Mol. Mass.:
314.448
SMILES:
CN(C)C(CNC(=S)Nc1cccc(C)c1)c1cccnc1
Structure:
Search PDB for entries with ligand similarity: