Target
Endoribonuclease toxin MazF
Ligand
BDBM83557
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay
EC50
>99000±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM83557
Synonyms:
6-chloranyl-2-[(E)-2-(4-methoxyphenyl)ethenyl]chromen-4-one | 6-chloro-2-[(E)-2-(4-methoxyphenyl)ethenyl]-1-benzopyran-4-one | 6-chloro-2-[(E)-2-(4-methoxyphenyl)ethenyl]chromen-4-one | 6-chloro-2-[(E)-2-(4-methoxyphenyl)vinyl]-4H-chromen-4-one | 6-chloro-2-[(E)-2-(4-methoxyphenyl)vinyl]chromone | MLS000585393 | SMR000204156 | cid_6181973
Type:
Small organic molecule
Emp. Form.:
C18H13ClO3
Mol. Mass.:
312.747
SMILES:
COc1ccc(\C=C\c2cc(=O)c3cc(Cl)ccc3o2)cc1
Structure:
Search PDB for entries with ligand similarity: