Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM47570
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay Set 2
IC50
2470±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM47570
Synonyms:
(1Z)-1-[[2-[4-(1H-imidazol-2-yl)phthalazin-1-yl]hydrazinyl]methylidene]naphthalen-2-one | (1Z)-1-[[N'-[4-(1H-imidazol-2-yl)phthalazin-1-yl]hydrazino]methylene]naphthalen-2-one | (1Z)-1-[[[4-(1H-imidazol-2-yl)-1-phthalazinyl]hydrazo]methylidene]-2-naphthalenone | MLS000564044 | SMR000151639 | cid_11948738
Type:
Small organic molecule
Emp. Form.:
C22H16N6O
Mol. Mass.:
380.402
SMILES:
Oc1ccc2ccccc2c1CN=Nc1nnc(-c2ncc[nH]2)c2ccccc12 |w:13.15|
Structure:
Search PDB for entries with ligand similarity: