Reaction Details Report a problem with these data
Target
Sentrin-specific protease 8
Ligand
BDBM84032
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
7410±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84032
Synonyms:
3-[(E)-2-(4-fluorophenyl)ethenyl]-5-(2-iodanylphenyl)-1,2,4-oxadiazole | 3-[(E)-2-(4-fluorophenyl)ethenyl]-5-(2-iodophenyl)-1,2,4-oxadiazole | 3-[(E)-2-(4-fluorophenyl)vinyl]-5-(2-iodophenyl)-1,2,4-oxadiazole | MLS-0454392.0001 | cid_49852501
Type:
Small organic molecule
Emp. Form.:
C16H10FIN2O
Mol. Mass.:
392.1663
SMILES:
Fc1ccc(\C=C\c2noc(n2)-c2ccccc2I)cc1
Structure:
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