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Target
Sentrin-specific protease 8
Ligand
BDBM84049
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
1440±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84049
Synonyms:
(6E)-6-[3-[(E)-2-(4-chlorophenyl)ethenyl]-2H-1,2,4-oxadiazol-5-ylidene]-1-cyclohexa-2,4-dienone | (6E)-6-[3-[(E)-2-(4-chlorophenyl)ethenyl]-2H-1,2,4-oxadiazol-5-ylidene]cyclohexa-2,4-dien-1-one | (6E)-6-[3-[(E)-2-(4-chlorophenyl)vinyl]-2H-1,2,4-oxadiazol-5-ylidene]cyclohexa-2,4-dien-1-one | MLS-0454351.0002 | cid_16488883
Type:
Small organic molecule
Emp. Form.:
C16H11ClN2O2
Mol. Mass.:
298.724
SMILES:
Oc1ccccc1-c1nc(C=Cc2ccc(Cl)cc2)no1 |w:10.10|
Structure:
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