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Target
Beta-2 adrenergic receptor
Ligand
BDBM84206
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from Powderset1
EC50
10.2±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from Powderset1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84206
Synonyms:
MLS000064236 | N,4-dimethyl-N-[2-oxidanylidene-2-(4-pyridin-2-ylpiperazin-1-yl)ethyl]benzenesulfonamide | N,4-dimethyl-N-[2-oxo-2-(4-pyridin-2-ylpiperazin-1-yl)ethyl]benzenesulfonamide | N,4-dimethyl-N-[2-oxo-2-[4-(2-pyridinyl)-1-piperazinyl]ethyl]benzenesulfonamide | N,4-dimethyl-N-{2-oxo-2-[4-(2-pyridinyl)-1-piperazinyl]ethyl}benzenesulfonamide (non-preferred name) | N-[2-keto-2-[4-(2-pyridyl)piperazino]ethyl]-N,4-dimethyl-benzenesulfonamide | SMR000076255 | cid_2953239
Type:
Small organic molecule
Emp. Form.:
C19H24N4O3S
Mol. Mass.:
388.484
SMILES:
CN(CC(=O)N1CCN(CC1)c1ccccn1)S(=O)(=O)c1ccc(C)cc1
Structure:
Search PDB for entries with ligand similarity: