Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 22
Ligand
BDBM84581
Substrate
n/a
Meas. Tech.
PTP Assay
pH
6±0
Temperature
298.15±0 K
IC50
>5.0e+4±n/a nM
Citation
 Stuible, M; Zhao, L; Aubry, I; Schmidt-Arras, D; Böhmer, FD; Li, CJ; Tremblay, ML Cellular inhibition of protein tyrosine phosphatase 1B by uncharged thioxothiazolidinone derivatives. Chembiochem 8:179-86 (2007) [PubMed]  Article 
Target
Name:
Dual specificity protein phosphatase 22
Synonyms:
DUS22_HUMAN | DUSP22 | Dual specificity phosphatase 22 | Dual specificity protein phosphatase (MKPX) | Dual specificity protein phosphatase 22 | Dual specificity protein phosphatase 22 (VHX) | Dual specificity protein phosphatase VHX (VHX) | JSP1 | LMWDSP2 | MKPX | Mitogen-activated protein kinase phosphatase x | VHX
Type:
Protein
Mol. Mass.:
20915.83
Organism:
Homo sapiens (Human)
Description:
Q9NRW4
Residue:
184
Sequence:
MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILAAPGILKFWAFLRRL
  
Inhibitor
Name:
BDBM84581
Synonyms:
Thioxothiazolidinone derivative, 1
Type:
Small organic molecule
Emp. Form.:
C17H11ClN2O5S2
Mol. Mass.:
422.863
SMILES:
COc1cc(\C=C2/SC(=S)N(C2=O)c2cccc(Cl)c2)cc(c1O)N(=O)=O
Structure:
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