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Target
5-hydroxytryptamine receptor 6
Ligand
BDBM50280053
Substrate
n/a
Ki
100±n/a nM
Comments
PDSP_650
Citation
 Plassat, JL; Amlaiky, N; Hen, R Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Mol Pharmacol 44:229-36 (1993) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 6
Synonyms:
5-HT6 | 5-hydroxytryptamine receptor 6 | 5HT6R_MOUSE | Htr6
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47012.98
Organism:
MOUSE
Description:
5-HT6 HTR6 MOUSE::Q9R1C8
Residue:
440
Sequence:
MVPEPGPVNSSTPAWGPGPPPAPGGSGWVAAALCVVIVLTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTAPRALALILGAWSLAALASFLPLLLGWHELGKARTSAPGQCRLLASLPYVLVASGVTFFLPSGAICFTYCRILLAARKQAVQVASLTTGTATAGQALETLQVPRTPRPGMESADSRRLTTKHSRKALKASLTLGILLSMFFVTWLPFFVASIAQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFVPCVHCPPEHRASPASPSMWTSHSGARPGLSLQQVLPLPLPPNSDSDSASGGTSGLQLTAQLLLPGEATRDPPPPTRAPTVVNFFVTDSVEPEIRQHPLGSPMN
  
Inhibitor
Name:
BDBM50280053
Synonyms:
7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((2R,5S,10bS)-10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide | CHEMBL18329 | DHC | DIHYDROERGOCRYPTINE
Type:
Small organic molecule
Emp. Form.:
C32H43N5O5
Mol. Mass.:
577.7143
SMILES:
CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)C3CC4C(Cc5c[nH]c6cccc4c56)N(C)C3)(O[C@@]2(O)C2CCCN2C1=O)C(C)C
Structure:
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