Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50001156
Substrate
n/a
Meas. Tech.
ChEBML_96965
IC50
1500±n/a nM
Citation
 Labaudinière, R; Hilboll, G; Leon-Lomeli, A; Terlain, B; Cavy, F; Parnham, M; Kuhl, P; Dereu, N Omega-[(omega-arylalkyl)thienyl]alkanoic acids: from specific LTA4 hydrolase inhibitors to LTB4 receptor antagonists. J Med Chem 35:3170-9 (1992) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50001156
Synonyms:
7-[5-Methyl-3-(3-phenyl-propyl)-thiophen-2-yl]-heptanoic acid | CHEMBL110708
Type:
Small organic molecule
Emp. Form.:
C21H28O2S
Mol. Mass.:
344.511
SMILES:
Cc1cc(CCCc2ccccc2)c(CCCCCCC(O)=O)s1
Structure:
Search PDB for entries with ligand similarity: