Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 4
Ligand
BDBM50240829
Substrate
n/a
Meas. Tech.
ChEMBL_1669002 (CHEMBL4018890)
EC50
0.500000±n/a nM
Citation
 Schubert, M; Stichel, J; Du, Y; Tough, IR; Sliwoski, G; Meiler, J; Cox, HM; Weaver, CD; Beck-Sickinger, AG Identification and Characterization of the First Selective Y J Med Chem 60:7605-7612 (2017) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 4
Synonyms:
NPY-Y4 | NPY4-R | NPY4R | NPY4R_HUMAN | PP1 | PPYR1 | Pancreatic polypeptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42207.58
Organism:
Homo sapiens (Human)
Description:
NPY-Y4 PPYR1 HUMAN::P50391
Residue:
375
Sequence:
MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRRLQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTEVSKGSLRLSGRSNPI
  
Inhibitor
Name:
BDBM50240829
Synonyms:
CHEMBL3559801
Type:
Small organic molecule
Emp. Form.:
C16H24O2
Mol. Mass.:
248.3606
SMILES:
CC(C)(C)c1ccc(OC2CCCCC2O)cc1
Structure:
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