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Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50002435
Substrate
n/a
Meas. Tech.
ChEMBL_98636 (CHEMBL711836)
IC50
2200±n/a nM
Citation
 Connor, DT; Cetenko, WA; Mullican, MD; Sorenson, RJ; Unangst, PC; Weikert, RJ; Adolphson, RL; Kennedy, JA; Thueson, DO; Wright, CD Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents. J Med Chem 35:958-65 (1992) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_HUMAN | CYSLT1 | CYSLTR1 | Cysteinyl leukotriene D4 receptor | Cysteinyl leukotriene receptor | Cysteinyl leukotriene receptor 1 | HG55 | HMTMF81 | LTD4 receptor | Leukotriene Cysteinyl 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38565.16
Organism:
Homo sapiens (Human)
Description:
Leukotriene Cysteinyl 1 CYSLTR1 HUMAN::Q9Y271
Residue:
337
Sequence:
MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV
  
Inhibitor
Name:
BDBM50002435
Synonyms:
3-Isopropoxy-5-methoxy-benzo[b]thiophene-2-carboxylic acid (1H-tetrazol-5-yl)-amide | CHEMBL302045
Type:
Small organic molecule
Emp. Form.:
C14H15N5O3S
Mol. Mass.:
333.366
SMILES:
COc1ccc2sc(C(=O)Nc3nnn[nH]3)c(OC(C)C)c2c1
Structure:
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