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TargetAdenosine receptor
LigandBDBM50242085
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1671313
Ki 5.5±n/a nM
Citation Basu, SBarawkar, DARamdas, VPatel, MWaman, YPanmand, AKumar, SThorat, SNaykodi, MGoswami, AReddy, BSPrasad, VChaturvedi, SQuraishi, AMenon, SPaliwal, SKulkarni, AKarande, VGhosh, IMustafa, SDe, SJain, VBanerjee, ERRouduri, SRPalle, VPChugh, AMookhtiar, KA Design and synthesis of novel xanthine derivatives as potent and selective A Eur J Med Chem134:218-229 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor
Name:Adenosine receptor
Synonyms:ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:36341.22
Organism:Homo sapiens (Human)
Description:n/a
Residue:332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50242085
NameBDBM50242085
Synonyms:CHEMBL4080646
TypeSmall organic molecule
Emp. Form.C24H23F3N6O3
Mol. Mass.500.473
SMILESCCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cnn(CC#Cc2ccc(OC(F)(F)F)cc2)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a