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TargetCarbonic anhydrase
LigandBDBM50163858
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1673909
Kd 1±n/a nM
Citation Linkuvien?, VTalibov, VODanielson, UHMatulis, D Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design. J Med Chem61:2292-2302 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase
Name:Carbonic anhydrase
Synonyms:CA-VII | CA7 | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:Enzyme
Mol. Mass.:29664.11
Organism:Homo sapiens (Human)
Description:Human cloned isozyme.
Residue:264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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  Blast E-value cutoff:
BDBM50163858
NameBDBM50163858
Synonyms:CHEMBL2443188 | carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 7
TypeSmall organic molecule
Emp. Form.C12H10ClN3O3S2
Mol. Mass.343.809
SMILESNS(=O)(=O)c1ccc(cc1Cl)C(=O)CSc1ncccn1
Structure
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n/a