Reaction Details Report a problem with these data
Target
Phospholipase A2, major isoenzyme
Ligand
BDBM50004676
Substrate
n/a
Meas. Tech.
ChEBML_155878
IC50
>1000000±n/a nM
Citation
 Wright, SW; Harris, RR; Collins, RJ; Corbett, RL; Green, AM; Wadman, EA; Batt, DG Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity. J Med Chem 35:3148-55 (1992) [PubMed]  Article 
Target
Name:
Phospholipase A2, major isoenzyme
Synonyms:
Group IB phospholipase A2 | PA21B_PIG | PLA2G1B | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2
Type:
Hydrolase; monomer or homodimer
Mol. Mass.:
16279.83
Organism:
Sus scrofa (pig)
Description:
Purchased from Sigma.
Residue:
146
Sequence:
MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPVDELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNCDRNAAICFSKAPYNKEHKNLDTKKYC
  
Inhibitor
Name:
BDBM50004676
Synonyms:
1-(4-Fluoro-phenyl)-2-imidazol-1-yl-1-(4-pyridin-4-yl-phenyl)-ethanol | CHEMBL321024
Type:
Small organic molecule
Emp. Form.:
C22H18FN3O
Mol. Mass.:
359.3962
SMILES:
OC(Cn1ccnc1)(c1ccc(F)cc1)c1ccc(cc1)-c1ccncc1
Structure:
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