Reaction Details Report a problem with these data
Target
Muscarinic acetylcholine receptor
Ligand
BDBM50004731
Substrate
n/a
Meas. Tech.
ChEMBL_138312 (CHEMBL743823)
Kd
100000±n/a nM
Citation
 Nilsson, BM; Vargas, HM; Hacksell, U Urea and 2-imidazolidone derivatives of the muscarinic agents oxotremorine and N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide. J Med Chem 35:3270-9 (1992) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor
Synonyms:
GPM3 | Muscarinic acetylcholine receptor M3
Type:
n/a
Mol. Mass.:
66272.13
Organism:
Cavia porcellus
Description:
n/a
Residue:
587
Sequence:
MTLHSNSTTLPLFPNISTSWIHSPSEAGLPPGTVTHFGSYNISQAAGNFSSLNGTTSDPLGGHTIWQVVFIAFLTGFLALVTIIGNILVIVSFKVNKQLKHVNNYFLLSLADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSLKHSSRRKYSRCHFWFATKSWKPNAGQMDQDHSSSDSWNNYDAAASLENSASDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEDLEPMDMERNASKPQTQKSMDDGGSFQKSFSNLPIQLESTMDTAKTSDANSSVSKTMATLPLSFKEATLAKRFALRTRSQITKRKRMSLIKEKRAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRNTFKMLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
  
Inhibitor
Name:
BDBM50004731
Synonyms:
3-(4-Pyrrolidin-1-yl-but-2-ynyl)-imidazolidine-2,4-dione | CHEMBL111467
Type:
Small organic molecule
Emp. Form.:
C11H15N3O2
Mol. Mass.:
221.2557
SMILES:
Oc1c[nH]c(=O)n1CC#CCN1CCCC1
Structure:
Search PDB for entries with ligand similarity: