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Target
Platelet-activating factor receptor
Ligand
BDBM50005240
Substrate
n/a
Meas. Tech.
ChEBML_164926
IC50
690±n/a nM
Citation
 Carceller, E; Merlos, M; Giral, M; Bartrolí, J; García-Rafanell, J; Forn, J 4-substituted 2-alkoxytetrahydrofurans as potent and long-lasting PAF antagonists. J Med Chem 35:676-83 (1992) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50005240
Synonyms:
2-({Acetyl-[5-(3-methyl-butoxy)-tetrahydro-furan-3-ylmethoxycarbonyl]-amino}-methyl)-1-ethyl-pyridinium; iodide | CHEMBL161674
Type:
Small organic molecule
Emp. Form.:
C21H33N2O5
Mol. Mass.:
393.4966
SMILES:
CC[n+]1ccccc1CN(C(C)=O)C(=O)OCC1COC(C1)OCCC(C)C
Structure:
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