Reaction Details Report a problem with these data
Target
Advanced glycosylation end product-specific receptor
Ligand
BDBM50249579
Substrate
n/a
Meas. Tech.
ChEBML_1680057
Kd
1.000000±n/a nM
Citation
 Bongarzone, S; Savickas, V; Luzi, F; Gee, AD Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective. J Med Chem 60:7213-7232 (2017) [PubMed]  Article 
Target
Name:
Advanced glycosylation end product-specific receptor
Synonyms:
AGER | RAGE | RAGE_HUMAN | Receptor for advanced glycosylation end products
Type:
PROTEIN
Mol. Mass.:
42800.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1339877
Residue:
404
Sequence:
MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEAWKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQIPGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRHPETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQLVVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYSCVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGVILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP
  
Inhibitor
Name:
BDBM50249579
Synonyms:
CHEMBL1477694 | US10729695, Compound CB-3
Type:
Small organic molecule
Emp. Form.:
C23H21N3O
Mol. Mass.:
355.4323
SMILES:
Cc1nc2ccccc2n1CC(O)Cn1c2ccccc2c2ccccc12
Structure:
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