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Target
Cholecystokinin receptor type A
Ligand
BDBM50005464
Substrate
n/a
Meas. Tech.
ChEBML_47649
Ki
>4000±n/a nM
Citation
 van der Bent, A; Blommaert, AG; Melman, CT; IJzerman, AP; van Wijngaarden, I; Soudijn, W Hybrid cholecystokinin-A antagonists based on molecular modeling of lorglumide and L-364,718. J Med Chem 35:1042-9 (1992) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50005464
Synonyms:
1-(4-Chloro-phenyl)-3-[2-(10,11-dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-ethyl]-urea | CHEMBL275031
Type:
Small organic molecule
Emp. Form.:
C24H21ClN2O
Mol. Mass.:
388.889
SMILES:
Clc1ccc(-[#7]-[#6](=O)-[#7]-[#6]\[#6]=[#6]-2\c3ccccc3-[#6]-[#6]-c3ccccc-23)cc1
Structure:
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