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Target
Pancreatic alpha-amylase
Ligand
BDBM50005680
Substrate
n/a
Meas. Tech.
ChEBML_34104
IC50
2700±n/a nM
Citation
 Leader, H; Gordon, RK; Baumgold, J; Boyd, VL; Newman, AH; Smejkal, RM; Chiang, PK Muscarinic receptor subtype specificity of (N,N-dialkylamino)alkyl 2-cyclohexyl-2-phenylpropionates: cylexphenes (cyclohexyl-substituted aprophen analogues). J Med Chem 35:1290-5 (1992) [PubMed]  Article 
Target
Name:
Pancreatic alpha-amylase
Synonyms:
1,4-alpha-D-glucan glucanohydrolase | AMYP_RAT | Amy2 | PA
Type:
PROTEIN
Mol. Mass.:
57186.64
Organism:
Rattus norvegicus
Description:
ChEMBL_34101
Residue:
508
Sequence:
MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFGGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWYFNDNKCNGEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNNLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRRTRNFQNGKDVNDWIGPPNNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL
  
Inhibitor
Name:
BDBM50005680
Synonyms:
2-Cyclohexyl-2-phenyl-propionic acid 5-diethylamino-pentyl ester | CHEMBL24369
Type:
Small organic molecule
Emp. Form.:
C24H39NO2
Mol. Mass.:
373.572
SMILES:
CCN(CC)CCCCCOC(=O)C(C)(C1CCCCC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: