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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50006246
Substrate
n/a
Meas. Tech.
ChEMBL_222720 (CHEMBL844388)
Ki
1600±n/a nM
Citation
 De Amici, M; Dallanoce, C; De Micheli, C; Grana, E; Barbieri, A; Ladinsky, H; Schiavi, G; Zonta, F Synthesis and pharmacological investigation of the enantiomers of muscarone and allomuscarone. J Med Chem 35:1915-20 (1992) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50006246
Synonyms:
CHEMBL56734 | Trimethyl-(5-methyl-4-oxo-tetrahydro-furan-2-ylmethyl)-ammonium; iodide
Type:
Small organic molecule
Emp. Form.:
C9H18NO2
Mol. Mass.:
172.2442
SMILES:
C[C@@H]1O[C@H](C[N+](C)(C)C)CC1=O
Structure:
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