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Target
Gastrin/cholecystokinin type B receptor
Ligand
BDBM50006841
Substrate
n/a
Meas. Tech.
ChEBML_48261
IC50
9100±n/a nM
Citation
 Yu, MJ; McCowan, JR; Mason, NR; Deeter, JB; Mendelsohn, LG Synthesis and X-ray crystallographic analysis of quinazolinone cholecystokinin/gastrin receptor ligands. J Med Chem 35:2534-42 (1992) [PubMed]  Article 
Target
Name:
Gastrin/cholecystokinin type B receptor
Synonyms:
Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49196.59
Organism:
MOUSE
Description:
Cholecystokinin A CCKBR MOUSE::P56481
Residue:
453
Sequence:
MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGLISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCYVQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANTWRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
  
Inhibitor
Name:
BDBM50006841
Synonyms:
2-[2-(1H-Indol-3-yl)-1-methyl-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one | CHEMBL85393
Type:
Small organic molecule
Emp. Form.:
C28H27N3O2
Mol. Mass.:
437.5329
SMILES:
CC(C)Oc1cccc(c1)-n1c(nc2ccccc2c1=O)C(C)Cc1c[nH]c2ccccc12
Structure:
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